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age C31 integrase: a new tool in plastid genome engineering. Trends in Plant Science (2005) 10:1¨C3.

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Thomason LC, Calendar R, Ow DW. Gene insertion and replacement in Schizosaccharomyces pombe mediated by the Streptomyces bacteriophage C31 site-specific recombination system. Mol. Gen. Genom (2001) 265:1031¨C1038.

Nkrumah LJ, Muhle RA, Moura PA, Ghosh P, Hatfull GF, Jacobs WR Jr, Fidock DA. Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase. Nat. Methods (2006) 3:615¨C621.

Thyagarajan B, Olivares EC, Hollis RP, Ginsburg DS, Calos MP. Site-specific genomic integration in mammalian cells mediated by phage C31 integrase. Mol Cell Biol (2001) 21:3926¨C3934.

Groth AC, Olivares EC, Thyagarajan B, Calos MP. A phage integrase directs efficient site-specific integration in human cells. Proc. Natl Acad. Sci. USA (2000) 97:5995¨C6000.

Olivares EC, Hollis RP, Chalberg TW, Meuse L, Kay MA, Calos MP. Site-specific genomic integration produces therapeutic Factor IX levels in mice. Nat. Biotechnol (2002) 20:1124¨C1128.

Held PK, Olivares EC, Aguilar CP, Finegold M, Calos MP, Grompe M. In vivo correction of murine hereditary tyrosinemia type I by C31 integrase-mediated gene delivery. Mol. Ther (2005) 11:399¨C408.

Portlock JL, Keravala A, Bertoni C, Lee S, Rando TA, Calos MP. Long-term increase in mVEGF164 in mouse hindlimb muscle mediated by phage C31 integrase after nonviral DNA delivery. Hum. Gene Ther (2006) 17:871¨C876.

Keravala A, Portlock JL, Nash JA, Vitrant DG, Robbins PD, Calos MP. C31 integrase mediates integration in cultured synovial cells and enhances gene expression in rabbit joints. J. Gene Med (2006) 8:1008¨C1017.

Bertoni C, Jarrahian S, Wheeler TM, Li Y, Olivares EC, Calos MP, Rando TA. Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration. Proc. Natl. Acad. Sci. USA (2006) 103:419¨C424.

Thorpe HM, Smith MCM. In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family. Proc. Natl Acad. Sci. USA (1998) 95:5505¨C5510.

Ghosh P, Kim AI, Hatfull GF. The orientation of mycobacteriophage Bxb1 integration is solely dependent on the central dinucleotide of attP and attB. Mol. Cell (2003) 12:1101¨C1111.

Azaro MA, Landy A. Mobile DNA II¡ªCraig NL, Craigie R, Gellert M, Lambowitz AM, eds. (2002) Washington D.C.: ASM Press. 118¨C148.

Ghosh P, Wasil LR, Hatfull GF. Control of phage Bxb1 excision by a novel recombination directionality factor. PLoS Biol (2006) 4:e186.

Smith MCM, Thorpe HM. Diversity in the serine recombinases. Mol. Microbiol (2002) 44:299¨C307.

Craig NL. Mobile DNA II¡ªCraig NL, Craigie R, Gellert M, Lambowitz AM, eds. (2002) Washington DC: American Society for Microbiology. 3¨C11.

Biswas T, Aihara H, Radman-Livaja M, Filman D, Landy A, Ellenberger T. A structural basis for allosteric control of DNA recombination by lambda integrase. Nature (2005) 435:1059¨C1066.

Radman-Livaja M, Biswas T, Ellenberger T, Landy A, Aihara H. DNA arms do the legwork to ensure the directionality of lambda site-specific recombination. Curr. Opin. Struct. Biol (2006) 16:42¨C50.

Grindley NDF. Mobile DNA II¡ªCraig NL, Craigie R, Gellert M, Lambowitz AM, eds. (2002) Washington: ASM Press. 272¨C302.

Yang W, Steitz TA. Crystal-structure of the site-specific recombinase gamma-delta resolvase complexed with a 34bp cleavage site. Cell (1995) 82:193¨C207.

Ghosh P, Pannunzio NR, Hatfull GF. Synapsis in phage Bxb1 integration: selection mechanism for the correct pair of recombination sites. J. Mol. Biol (2005) 349:331¨C348.

Smith MCA, Till R, Brady K, Soultanas P, Thorpe H, Smith MCM. Synapsis and DNA cleavage in C31 integrase-mediated site-specific recombination. Nucleic Acids Res (2004) 32:2607¨C2617.

Smith MCA, Till R, Smith MCM. Switching the polarity of a bacteriophage integration system. Mol. Microbiol (2004) 51:1719¨C1728.

Thorpe HM, Wilson SE, Smith MCM. Control of directionality in the site-specific recombination system of the Streptomyces phage C31. Mol. Microbiol (2000) 38:232¨C241.

Adams V, Lucet IS, Tynan FE, Chiarezza M, Howarth PM, Kim J, Rossjohn J, Lyras D, Rood JI. Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function. Mol. Microbiol (2006) 60:591¨C601.

Crellin PK, Rood JI. The resolvase/invertase domain of the site-specific recombinase TnpX is functional and recognizes a target sequence that resembles the junction of the circular form of the Clostridium perfringens transposon Tn4451. J. Bacteriol (1997) 179:5148¨C5156.

Wang H, Mullany P. The large resolvase TndX is required and sufficient for integration and excision of derivatives of the novel conjugative transposon Tn5397. J. Bacteriol (2000) 182:6577¨C6583.

Johnson RC. Mobile DNA II¡ªCraig NL, Craigie R, Gellert M, Lambowitz AM, eds. (2002) Washington DC: ASM Press. 230¨C271.

Li W, Kamtekar S, Xiong Y, Sarkis GJ, Grindley NDF, Steitz TA. Structure of a synaptic gammadelta resolvase tetramer covalently linked to two cleaved DNAs. Science (2005) 309:1210¨C1215.

Nollmann M, He J, Byron O, Stark WM. Solution structure of the Tn3 resolvase-crossover site synaptic complex. Mol. Cell (2004) 16:127¨C137.

Stark WM, Boocock MR, Sherratt DJ. Catalysis by site-specific recombinases. Trends Genet (1992) 8:432¨C439.

Kamtekar S, Ho RS, Cocco MJ, Li W, Wenwieser SV, Boocock MR, Grindley NDF, Steitz TA. Implications of structures of synaptic tetramers of gamma delta resolvase for the mechanism of recombination. Proc. Natl. Acad. Sci. USA (2006) 103:10642¨C10647.

Stark WM, Grindley NDF, Hatfull GF, Boocock MR. Resolvase-catalyzed reactions between sites differing in the central dinucleotide of subsite-I. EMBO J (1991) 10:3541¨C3548.

Kuhstoss S, Rao RN. Analysis of the integration function of the streptomycete bacteriophage c31. J. Mol. Biol (1991) 222:897¨C908.

Breuner A, Brondsted L, Hammer K. Resolvase-like recombination performed by the TP901-1 integrase. Microbiology (2001) 147:2051¨C2063.

Combes P, Till R, Bee S, Smith MCM. The streptomyces genome contains multiple pseudo-attB sites for the ()C31-encoded site-specific recombination system. J. Bacteriol (2002) 184:5746¨C5752.

Chalberg TW, Portlock JL, Olivares EC, Thyagarajan B, Kirby PJ, Hillman RT, Hoelters J, Calos MP. Integration specificity of phage C31 integrase in the human genome. J. Mol. Biol (2006) 357:28¨C48.

Murry J, Sassetti CM, Moreira J, Lane J, Rubin EJ. A new site-specific integration system for mycobacteria. Tuberculosis (Edinb) (2005) 85:317¨C323.

Sambrook J, Russell DW. edn. In: Molecular Cloning: A Laboratory Manual (2001) 3rd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.

Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem (1976) 72:248¨C254.

Lucet IS, Tynan FE, Adams V, Rossjohn J, Lyras D, Rood JI. Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens. J. Biol. Chem (2005) 280:2503¨C2511.

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